Sherona graduated from the University of California, Los Angeles in 2008, with her MSN/dual program (acute care nurse practitioner/clinical nurse specialist). She has been working at Ronald Reagan UCLA Medical Center since 2003 as a registered nurse in the transplantation unit focusing on liver, kidney, pancreas, and small bowel transplantations. She also worked at the transitional transplantation care unit in which the majority of those critically ill patients were seen soon after receiving abdominal organ transplantation.

In 2010, Sherona joined the UCLA Pfleger Liver Institute and Asian Liver Cancer Center working as an outpatient hepatology nurse practitioner specializing in liver diseases and hepatocellular carcinoma. Since 2013, she has had six research papers published in Liver International, Journal of Clinical Gastroenterology, Clinical Transplant, and Journal of Clinical and Translational Hepatology. In early 2016, Sherona was invited as a guest speaker to teach overseas and at the UCLA MECN (Master Entry Clinical Nurse) program. She also participates in community service projects to screen for hepatitis C in a local church. Her clinical interests include hepatitis B, hepatitis C, biliary liver diseases, autoimmune liver diseases, fatty liver disease, drug-induced liver disease, and hepatocellular carcinoma.